The human brain possesses an extraordinary ability to rewire itself.
And we know that the brain can remap functions from one area to another following injury
– often dramatically.
And if we interface properly we can amplify and guide this rewiring process.
But – the brain is iontronic.
Therefore the ultimate neuro-recovery neural interface is one that recognizes this
and insists on creating an iontronic-based brain machine interface.
Panaxium is the world-leader in microscale iontronic technologies.
A multidisciplinary team with deep technical expertise in
organic bioelectronics, chemistry, materials science,
neuroscience, machine learning, and microsystem design.
A revolutionary approach to medicine requires bold creativity,
precision, a desire for improving lives, and the audacity to
continuously challenge and improve the science of healing.
Our Clinical Advisors & Partners
An Extraordinary Network
Top neurosurgeons, neurologists, and brain-machine interface and iontronics scientists
around the world to solve one of the most important challenges in medicine.
around the world to solve one of the most important challenges in medicine.
Professor George Malliaras, PhD
PRINCIPAL SCIENTIFIC ADVISOR
UNIVERSITY OF CAMBRIDGE
Professor George Malliaras, the Prince Philip Professor of Technology at the University of Cambridge, is an internationally-renowned scholar in the field of bioelectronics and a pioneer in the field of polymer bioelectronics. George focuses his research on the design and validation of conductive polymer devices to interface with the brain with the aim of understanding and treating neurological disorders, as well as the development of electronic devices and circuits that mimic computational features of the human brain.
Dr. Róisín M. Owens, PhD
PRINCIPAL SCIENTIFIC ADVISOR
UNIVERSITY OF CAMBRIDGE
Dr. Róisín M. Owens is Group Leader for the BioElectronic Systems Technologies (B.E.S.T.) Group at the University of Cambridge. Róisín’s expertise is in the generation of biomimetic biological models with integrated electronic devices for monitoring or modulation, and to develop platforms that can be predictive of real biological systems.
Dr. Gilles Huberfeld, MD, PhD
CLINICAL ADVISOR
HÔPITAL FONDATION ADOLPHE DE ROTHSCHILD
Dr. Gilles Huberfeld, MD, PhD, is a clinical neurologist at the Rothschild Foundation Hospital (Paris) and Neuroscience researcher at Collège de France/ PSL, Paris dedicated to electrophysiology, particularly pertaining to epilepsy, brain injuries (with a focus on gliomas), and ion signaling affecting neural excitability. Dr. Huberfeld collaborates and advises Panaxium regarding device-tissue electrophysiology, and in the development of Panaxium’s technology for intraoperative monitoring using high-resolution electrocorticography.
Dr. Steven C. Cramer, MD
CLINICAL ADVISOR
UCLA
Dr. Steven C. Cramer, MD is a world-renowned neurologist and Professor of Neurology at the University of California, Los Angeles, Director of Research at California Rehabilitation Institute, co-PI of the NIH StrokeNet clinical trials network, and a Section Editor at the medical journal Stroke. Dr. Cramer graduated with Highest Honors from University of California, Berkeley; received his medical degree from University of Southern California; did a residency in internal medicine at UCLA; and a residency in neurology plus a fellowship in cerebrovascular disease at Massachusetts General Hospital. He earned a Masters Degree in Clinical Investigation from Harvard Medical School.
Professor Numa Dancause, PhD
CLINICAL ADVISOR
UNIVERSITY OF MONTREAL
Professor Numa Dancause is a Professor in the Department of Neurosciences at the University of Montreal where he conducts research on premotor cortex function and on cortical plasticity following brain injury. He uses multiple electrophysiological and neuroanatomical techniques in combination with behavioral analyses in both large and small animal models. Dr. Dancause will apply his world-class expertise to refine the design of Panaxium’s pre-clinical and clinical studies, and will conduct groundbreaking collaborative work in his lab using Panaxium’s devices.
Dr. Allen Waziri, MD
CLINICAL ADVISOR
ICE NEUROSYSTEMS
Dr. Allen Waziri, a practicing neurosurgeon and translational neuroscientist, is the CEO and Co-Founder of iCE Neurosystems. Allen’s research focuses on approaches to augment EEG acquisition for enhancing detection and predictive analysis of physiological alterations impacting neuronal health following severe brain injury. His lab also utilizes human tissue-mediated studies to explore immunotherapeutic and anti-invasive therapies for malignant brain tumors.
Dr. Jonathan Rivnay, PhD
SCIENTIFIC ADVISOR
NORTHWESTERN UNIVERSITY
Dr. Jonathan Rivnay leads the Rivnay Research Group at Northwestern University, renowned for designing and developing new materials and devices to facilitate the seamless integration of sensing / actuation technologies with cells and tissue to enable improvements in diagnosis and therapy. Jonathan’s research focuses on active materials such as conducting polymers which exhibit mixed ionic and electronic conduction, which aids in closing the signaling gap inherent to the bioelectronic interface.
Dr. Dion Khodagholy, PhD
SCIENTIFIC ADVISOR
COLUMBIA UNIVERSITY
Dr. Dion Khodagholy is an assistant professor in the Department of Electrical Engineering, School of Engineering and Applied Science at Columbia University. Dion’s research aims to use unique properties of materials for the purpose of designing and developing novel electronic devices that allow efficient interaction with biological substrates, specifically neural networks at the brain.
Dr. Brian Litt, MD
CLINICAL ADVISOR – NEUROLOGY &
BIOMEDICAL ENGINEERING
UNIVERSITY OF PENNSYLVANIA
Dr. Brian Litt is Professor of Neurology, Neurosurgery, and Bioengineering at the University of Pennsylvania. He received his MD at the Johns Hopkins School of Medicine, where he also completed his residency in Neurology. He is the Director, Penn Center for Neuroengineering and Therapeutics, Penn Epilepsy Center, Penn Health-Tech. Dr. Litt’s focus is on translating neuro- engineering research directly into patient care through a collaboration between neurology, neurosurgery, neuroscience, psychology, and engineering.
Dr. DJ Cook, MD, PhD
PRINCIPAL INVESTIGATOR,
PRECLINICAL TRIALS
QUEEN’S UNIVERSITY
Dr. D.J. Cook is a neurosurgeon at Kingston General Hospital, Queen’s University, and renowned neuroscientist specializing in how the brain adapts after injury, in particular after stroke and traumatic brain injury. Dr. Cook received his MD and PhD in Neuroscience from the University of Toronto, and completed a fellowship in cerebrovascular surgery at Stanford University. Dr. Cook is a faculty member at Queen’s University and the University of Minnesota.
Dr. Taufik Valiante, MD
CLINICAL ADVISOR
TORONTO GENERAL
Dr. Taufik Valiante graduated from the MD/PhD program at the University of Toronto in 1997 and completed an epilepsy neurosurgery fellowship at the University of Washington, Seattle. He is currently the Director of the Surgical Epilepsy Program at the Krembil Neuroscience Center, Director of the Center for Advancing Neurotechnological Innovation to Application (CRANIA), a Scientist at the Krembil Research Institute, and has a cross-appointment at the Institute of Biomaterials and Biomedical Engineering. His neurosurgical staff appointment is at the Toronto Western Hospital, and he is currently Associate Professor of Neurosurgery at the University of Toronto.
Dr. Rod O’Connor, PhD
SCIENTIFIC ADVISOR
EMSE
Dr. Rodney P. O'Connor is a cellular biophysicist, bioelectrician, neurotechnologist, neuroscientist, and professor. He currently works at the Département de Bioélectronique (BEL), George Charpak Campus, Provence, École Nationale Supérieure des Mines de Saint-Étienne. Rodney does research in Cancer Research, Bioelectronics, Biotechnology and Neuroscience. His current project is 'Oncoelectronics.'
Our Clinical Advisors & Partners
An Extraordinary Network
Top neurosurgeons, neurologists, and brain-machine interface and iontronics scientists around the world to solve one of the most important challenges in medicine.
Professor George Malliaras, PhD
PRINCIPAL SCIENTIFIC ADVISOR
UNIVERSITY OF CAMBRIDGE
Professor George Malliaras, the Prince Philip Professor of Technology at the University of Cambridge, is an internationally-renowned scholar in the field of bioelectronics and a pioneer in the field of polymer bioelectronics. George focuses his research on the design and validation of conductive polymer devices to interface with the brain with the aim of understanding and treating neurological disorders, as well as the development of electronic devices and circuits that mimic computational features of the human brain.
Dr. Róisín M. Owens, PhD
PRINCIPAL SCIENTIFIC ADVISOR
UNIVERSITY OF CAMBRIDGE
Dr. Róisín M. Owens is Group Leader for the BioElectronic Systems Technologies (B.E.S.T.) Group at the University of Cambridge. Róisín’s expertise is in the generation of biomimetic biological models with integrated electronic devices for monitoring or modulation, and to develop platforms that can be predictive of real biological systems.
Dr. Gilles Huberfeld, MD, PhD
CLINICAL ADVISOR
HÔPITAL FONDATION ADOLPHE DE ROTHSCHILD
Dr. Gilles Huberfeld, MD, PhD, is a clinical neurologist at the Rothschild Foundation Hospital (Paris) and Neuroscience researcher at Collège de France/ PSL, Paris dedicated to electrophysiology, particularly pertaining to epilepsy, brain injuries (with a focus on gliomas), and ion signaling affecting neural excitability. Dr. Huberfeld collaborates and advises Panaxium regarding device-tissue electrophysiology, and in the development of Panaxium’s technology for intraoperative monitoring using high-resolution electrocorticography.
Dr. Steven C. Cramer, MD
CLINICAL ADVISOR
UCLA
Dr. Steven C. Cramer, MD is a world-renowned neurologist and Professor of Neurology at the University of California, Los Angeles, Director of Research at California Rehabilitation Institute, co-PI of the NIH StrokeNet clinical trials network, and a Section Editor at the medical journal Stroke. Dr. Cramer graduated with Highest Honors from University of California, Berkeley; received his medical degree from University of Southern California; did a residency in internal medicine at UCLA; and a residency in neurology plus a fellowship in cerebrovascular disease at Massachusetts General Hospital. He earned a Masters Degree in Clinical Investigation from Harvard Medical School.
Professor Numa Dancause, PhD
CLINICAL ADVISOR
UNIVERSITY OF MONTREAL
Professor Numa Dancause is a Professor in the Department of Neurosciences at the University of Montreal where he conducts research on premotor cortex function and on cortical plasticity following brain injury. He uses multiple electrophysiological and neuroanatomical techniques in combination with behavioral analyses in both large and small animal models. Dr. Dancause will apply his world-class expertise to refine the design of Panaxium’s pre-clinical and clinical studies, and will conduct groundbreaking collaborative work in his lab using Panaxium’s devices.
Dr. Allen Waziri, MD
CLINICAL ADVISOR
ICE NEUROSYSTEMS
Dr. Allen Waziri, a practicing neurosurgeon and translational neuroscientist, is the CEO and Co-Founder of iCE Neurosystems. Allen’s research focuses on approaches to augment EEG acquisition for enhancing detection and predictive analysis of physiological alterations impacting neuronal health following severe brain injury. His lab also utilizes human tissue-mediated studies to explore immunotherapeutic and anti-invasive therapies for malignant brain tumors.
Dr. Jonathan Rivnay, PhD
SCIENTIFIC ADVISOR
NORTHWESTERN UNIVERSITY
Dr. Jonathan Rivnay leads the Rivnay Research Group at Northwestern University, renowned for designing and developing new materials and devices to facilitate the seamless integration of sensing / actuation technologies with cells and tissue to enable improvements in diagnosis and therapy. Jonathan’s research focuses on active materials such as conducting polymers which exhibit mixed ionic and electronic conduction, which aids in closing the signaling gap inherent to the bioelectronic interface.
Dr. Dion Khodagholy, PhD
SCIENTIFIC ADVISOR
COLUMBIA UNIVERSITY
Dr. Dion Khodagholy is an assistant professor in the Department of Electrical Engineering, School of Engineering and Applied Science at Columbia University. Dion’s research aims to use unique properties of materials for the purpose of designing and developing novel electronic devices that allow efficient interaction with biological substrates, specifically neural networks at the brain.
Dr. Brian Litt, MD
CLINICAL ADVISOR – NEUROLOGY & BIOMEDICAL
ENGINEERING
UNIVERSITY OF PENNSYLVANIA
Dr. Brian Litt is Professor of Neurology, Neurosurgery, and Bioengineering at the University of Pennsylvania. He received his MD at the Johns Hopkins School of Medicine, where he also completed his residency in Neurology. He is the Director, Penn Center for Neuroengineering and Therapeutics, Penn Epilepsy Center, Penn Health-Tech. Dr. Litt’s focus is on translating neuro- engineering research directly into patient care through a collaboration between neurology, neurosurgery, neuroscience, psychology, and engineering.
Dr. DJ Cook, MD, PhD
PRINCIPAL INVESTIGATOR,
PRECLINICAL TRIALS
QUEEN’S UNIVERSITY
Dr. D.J. Cook is a neurosurgeon at Kingston General Hospital, Queen’s University, and renowned neuroscientist specializing in how the brain adapts after injury, in particular after stroke and traumatic brain injury. Dr. Cook received his MD and PhD in Neuroscience from the University of Toronto, and completed a fellowship in cerebrovascular surgery at Stanford University. Dr. Cook is a faculty member at Queen’s University and the University of Minnesota.
Dr. Taufik Valiante, MD
CLINICAL ADVISOR
TORONTO GENERAL
Dr. Taufik Valiante graduated from the MD/PhD program at the University of Toronto in 1997 and completed an epilepsy neurosurgery fellowship at the University of Washington, Seattle. He is currently the Director of the Surgical Epilepsy Program at the Krembil Neuroscience Center, Director of the Center for Advancing Neurotechnological Innovation to Application (CRANIA), a Scientist at the Krembil Research Institute, and has a cross-appointment at the Institute of Biomaterials and Biomedical Engineering. His neurosurgical staff appointment is at the Toronto Western Hospital, and he is currently Associate Professor of Neurosurgery at the University of Toronto.
Dr. Rod O’Connor, PhD
SCIENTIFIC ADVISOR
EMSE
Dr. Rodney P. O'Connor is a cellular biophysicist, bioelectrician, neurotechnologist, neuroscientist, and professor. He currently works at the Département de Bioélectronique (BEL), George Charpak Campus, Provence, École Nationale Supérieure des Mines de Saint-Étienne. Rodney does research in Cancer Research, Bioelectronics, Biotechnology and Neuroscience. His current project is 'Oncoelectronics.'